Searchable abstracts of presentations at key conferences in endocrinology

ea0038p305 | Pituitary | SFEBES2015

In vitro effects of Imatinib on somatotrophinoma cell line

Gupta Prakamya , Rai Ashutosh , Sachdeva Naresh , Radotra Bishan Das , Bhansali Anil , Mukherjee Kanchan Kumar , Hota Debashish , Korbonits Marta , Dutta Pinaki

Introduction: Acromegaly is a neuroendocrine disorder caused by excessive secretion of growth hormone (GH). Current treatment includes surgery, radiotherapy and drugs like somatostatin or dopamine receptor agonist. In spite of combination of therapies cure rate is dismal. There is a quest for new therapeutic targets with optimal efficacy, least side effect without any cost constraints. Recently, a few reports have shown that tyrosine kinase inhibitor (Imatinib) causes growth f...